Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger

Mahamane Idi Issa Abdoulahi; Bakasso Sahabi; Alio Sanda Abdelkader; Ilagouma Amadou Tidjani; Yaou Chaïbou; Moctar Chaibou; Adamou Ibrahim Maman Laouali; Kiendrebeogo Martin; Sadou Hassimi

doi:doi:10.11648/j.jdmp.20200604.15

Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, Moctar Chaibou, Adamou Ibrahim Maman Laouali, Kiendrebeogo Martin, Sadou Hassimi

Published in Journal of Diseases and Medicinal Plants (Volume 6, Issue 4)

Received: 8 December 2020 Accepted: 16 December 2020 Published: 31 December 2020

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.

Published in	Journal of Diseases and Medicinal Plants (Volume 6, Issue 4)
DOI	10.11648/j.jdmp.20200604.15
Page(s)	92-97
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Phytochemistry, Salmonella typhimurium, Infectious Agents, Niger

References

[1]	Shannon E. Majowicz, Jennie Musto, Elaine Scallan, Frederick J. Angulo, Martyn Kirk, Sarah J. O'Brien, Timothy F. Jones, Aamir Fazil, and Robert M. Hoekstra. (2010). for the International Collaboration on Enteric Disease 'Burden of Illness' Studies: The Global Burden of Nontyphoidal Salmonella Gastroenteritis Clinical Infectious Diseases; 50: pp 882-889.
[2]	Alio Sanda A, Inoussa Maman M, Samna Soumana O, Bakasso Y. (2017). Diversité et dynamique des Salmonella isolées de la laitue (Lactuca sativa L.) dans les cultures maraîchères au Niger (Afrique de l’ouest). Journal of Applied Biosciences 119: 11917-11928. ISSN 1997-5902.
[3]	Alio Sanda Abdelkader, Samna Soumana Oumarou, Inoussa Maman Maârouhi, Soumana Abdou Boubacar, Moussa Hassane Ousseini, Bakasso Yacoubou. (2019). Diversity and Distribution of Salmonella Isolated from Poultry Offal in Niger (West Africa) International Journal of Microbiology and Biotechnology.
[4]	Alio Sanda A, Samna Soumana O, Bakasso Y. (2018). Epidemiology, diversity and resistance to antibiotics in Salmonella strains isolated from human in two cities of Niger Republic. International Journal of Current Research, (IJCR) Vol. 10, Issue, 02, pp. 65364-65370, February, 2018.
[5]	Konan KF, Guessennd KN, Oussou KR, Bahi C, Coulibaly A, Djaman AJ, DOSSO M. (2013). Effet antibactérien de l’extrait aqueux de l’écorce de Terminalia glaucescens Planch ex Benth (Combretaceae) sur la croissance in vitro des entérobactéries productrices de bêtalactamases à spectre élargi (EBLSE). Int. J. Biol. Chem. Sci., 8 (3): 1192-1201.
[6]	Kouadio N. J., Guessennd N. K., Kone M. W., Moussa B., Koffy. M I, Guede K. B., Yao K., Bakayoko A., Trabi H. F. Et Dosso M. (2015). Evaluation de l’activité des feuilles de Mallotus oppositifolius (Geisel.) Müll.-Arg (Euphorbiaceae) sur des bactéries multirésistantes et criblage phytochimique. Int. J. Biol. Chem. Sci. 9 (3): 1252-1262, June 2015. ISSN 1997-342X (Online), ISSN 1991-8631. Available online at http://ajol.info/index.php/ijbcs.
[7]	OMS, (2008). Statistique sanitaires mondiale 2008. (S. l.): World Health Organization.
[8]	Ciulei I. (1982). Pratical manuals on the industrialisation of medicinal and aromatic plants I. Methodology for analysis of vegetable drugs. Ministry of chemical industry, Bucherest, ROMANIA, p 67.
[9]	Wagner H., Bladt S. (1996). Plant drug analysis A. thin layer chromatography. Atlas. Second Edition Springer 384pages.
[10]	Cos P., Vlietinck A. J.; Vanden Berghe D., Maes L. (2006). Anti-infective potential of natural products: How to develop a stronger in vitro 'proof-of-concept'. Journal of Ethnopharmacology, 106, 290-302.
[11]	Bakasso S, (2009). Etudes phytochimiques et potentialités biologiques de cinq espèces d'Indigofera (Fabaceae) utilisées en médecine traditionnelle au Burkina Faso, Thèse Unique, Biochimie et chimie des substances naturelles. Université de Ouagadougou, Burkina Faso. 135 p.
[12]	Alio Sanda Abdel Kader, Inoussa Maman Maârouhi, Samna Soumana Oumarou, Alfa Keita Djibo, Halima Oumarou Diadié, Mahamane Idi Issa Abdoulahi and Bakasso Yacoubou. (2020). Evaluation of antibacterial activity from extract of three plant species on strains of salmonella in niger. World Journal of Pharmacy and Pharmaceutical Sciences, Volume 9, Issue 3, 462-481, ISSN 2278–4357.
[13]	Aliyu A. B., Ibrahim M. A., Musa A. M., Ibrahim H., Abdulkadir I. E. and Oyewale A. O., (2009). Evaluation of antioxydant activity of leave extract of Bauhinia rufescens Lam. (Caesalpiniaceae). Journal of Medicinal Plants Research Vol. 3 (8), (2009), pp. 563-567.
[14]	Yolidjé I., Keita D. A., Moussa I., Toumane A., Maarouhi I. M., Saley K., Jean-Luc P, T. Much, Ouamba J. M. (2019). Caractérisation Phytochimique et Activité Larvicide d’extraits Bruts de Plantes Issues de la Pharmacopée Traditionnelle du Niger sur les Larves d’Anopheles gambiae S. L. European Scientific Journal April 2019 edition Vol. 15, No. 12 ISSN: 1857 – 7881 (Print) e - ISSN 1857-7431.
[15]	Hima R. M., (2014). Etude des propriétés antibactériennes de deux plantes médicinales utilisées au Niger pour traiter les infections microbiennes. Mémoire de master, Université de Ouagadougou, Biotechnologie Microbienne et Cellulaire 61 p.
[16]	Nassirou R. S., Ibrahim M. L., Ilagouma A. T., Mahamadou A., Mamoudou M., Abdoulaye A., Oukem-Boyer O. O. M. et Khalid I., (2015), Évaluation in vitro de l’activité antiplasmodiale d’extraits de plantes issues de la pharmacopée traditionnelle du Niger, Journal of Applied Biosciences 89: 8291–8300, ISSN 1997–5902.
[17]	Kallo M. S., Adamou R., Sawadogo J., Mahamane A. A., Maarouhi I. M. et Khalid I. (2018). Enquête ethnobotanique et criblage phytochimique de quelques plantes tinctoriales du Niger en vue d’une valorisation en énergie solaire. Int. J. Biol. Chem. Sci. 12 (2): 867-883, ISSN 1997-342X (Online), ISSN 1991-8631, Available online at http://www.ifgdg.org.
[18]	Bilan O. S., Ilagouma A. T., Nassirou R. S., Moussa I., Hamo I. (2018). Enquête ethnobotanique et screening chimique des plantes utilisées comme fortifiants pour nourrisson au Niger. Annales de l'Université Abdou Moumouni, Série A – Tome XXIV pp. 125-133, déc. 2018.
[19]	Bruneton J., (2016). Pharmacognosie phytochimie-plantes médicinales; 5e édition©2016, Lavoisier, Paris; ISBN: 978-2-7430-2165-8; 1487 pages.
[20]	Mahamane IDI ISSA Abdoulahi, Bakasso Sahabi, Hama Garba Rahila, Hama Hamadou Habibou, Hassane Hamidou Zeinabou, Ilagouma Amadou Tidjani, Martin Kiendrebeogo and Hassimi Sadou. (2020). Phenolics contents and antioxidant activity of six medicinal plants used in the treatment of dentition related ailments in Niger. Journal of Pharmacognosy and Phytochemistry 2020; 9 (4): 1816-1821.
[21]	Odeyemi S. O. A. T., Agidigbi T. S., Adefemi S. O3. and Fasuan, (2014). Antibacterial activities of crude extracts of tithonia diversifolia against common environmental pathogenic bacteria, Internationl journal of science and technology The Experiment, vol. 20, no. 4, pp. 1421–1426.
[22]	Bruneton J (1999) Pharmacognsie. Photochimie, plantes médicinales. Ed Lavoisier, 1120 p.
[23]	Bolou G. E. K, Attioua B., N’guessan A. C., Coulibaly A., N’guessan J. D. Et Djaman A. J. (2011). Évaluation in vitro de l’activité antibactérienne des extraits de Terminalia glaucescens Planch. sur Salmonella typhi et Salmonella typhimurium. Bulletin de la Société Royale des Sciences de Liège, Vol. 80, 2011, p. 772–790.
[24]	Javanmardi J., Khalighi A., Bais H. P. And Vivanco J. M., (2002), Chemical characterization of basil (Osmium basilium L.) found in local occasion and used in traditional medicine in Iran, Journal of Agricultural and food chemistry, 50, p. 5878 - 5883.
[25]	Akomoun Blandine KAKPO, Eléonore YAYI, Bruno N. LENTA, Fidèle M. ASSOGBA, Placide M. TOCLO, Fabrice Fekam BOYOM, Lamine BABA-MOUSSA, and Joachim GBENOU (2019) Phytochemistry and anti-bacterial activity of thirteen plants used in traditional medicine to treat typhoid fever in Benin International Journal of Innovation and Applied Studies ISSN 2028-9324 Vol. 25 No. 3 Feb. 2019, pp. 1034-1047.
[26]	Raj NK, Spiral RM, Chaluvadi MR, Krishna DR. (2001) Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential. Indian J Pharmacol 33: 2–16.
[27]	Kil H. Y., Seong E. S., Ghimire B. K., Chung I. M., Kwon S. S., Goh E. J., Heo, K., Kim., M. J., Lim J. D., Lee D., Yu C. Y. (2009). Antioxidant and antimicrobial activities of crude sorghum extract. Food Chemistry. 115: 1234-1239.

Cite This Article

Plain Text BibTeX RIS

APA Style

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. (2020). Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. Journal of Diseases and Medicinal Plants, 6(4), 92-97. https://doi.org/10.11648/j.jdmp.20200604.15

Copy | Download

ACS Style

Mahamane Idi Issa Abdoulahi; Bakasso Sahabi; Alio Sanda Abdelkader; Ilagouma Amadou Tidjani; Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J. Dis. Med. Plants 2020, 6(4), 92-97. doi: 10.11648/j.jdmp.20200604.15

Copy | Download

AMA Style

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J Dis Med Plants. 2020;6(4):92-97. doi: 10.11648/j.jdmp.20200604.15

Copy | Download

@article{10.11648/j.jdmp.20200604.15,
  author = {Mahamane Idi Issa Abdoulahi and Bakasso Sahabi and Alio Sanda Abdelkader and Ilagouma Amadou Tidjani and Yaou Chaïbou and Moctar Chaibou and Adamou Ibrahim Maman Laouali and Kiendrebeogo Martin and Sadou Hassimi},
  title = {Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {6},
  number = {4},
  pages = {92-97},
  doi = {10.11648/j.jdmp.20200604.15},
  url = {https://doi.org/10.11648/j.jdmp.20200604.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20200604.15},
  abstract = {Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.},
 year = {2020}
}

Copy | Download

TY - JOUR
T1 - Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger
AU - Mahamane Idi Issa Abdoulahi
AU - Bakasso Sahabi
AU - Alio Sanda Abdelkader
AU - Ilagouma Amadou Tidjani
AU - Yaou Chaïbou
AU - Moctar Chaibou
AU - Adamou Ibrahim Maman Laouali
AU - Kiendrebeogo Martin
AU - Sadou Hassimi
Y1 - 2020/12/31
PY - 2020
N1 - https://doi.org/10.11648/j.jdmp.20200604.15
DO - 10.11648/j.jdmp.20200604.15
T2 - Journal of Diseases and Medicinal Plants
JF - Journal of Diseases and Medicinal Plants
JO - Journal of Diseases and Medicinal Plants
SP - 92
EP - 97
PB - Science Publishing Group
SN - 2469-8210
UR - https://doi.org/10.11648/j.jdmp.20200604.15
AB - Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.
VL - 6
IS - 4
ER -

Copy | Download

Author Information

Mahamane Idi Issa Abdoulahi

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Bakasso Sahabi

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Alio Sanda Abdelkader

Departement of Biology, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Ilagouma Amadou Tidjani

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Yaou Chaïbou
Moctar Chaibou

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Adamou Ibrahim Maman Laouali

Departement of Biology, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Kiendrebeogo Martin

Life and Earth Sciences Training And Research Unit, Faculty of Science and Technology, University of Ouagadougou, Ouagadougou, Burkina Faso
Sadou Hassimi

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. (2020). Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. Journal of Diseases and Medicinal Plants, 6(4), 92-97. https://doi.org/10.11648/j.jdmp.20200604.15

Copy | Download

ACS Style

Mahamane Idi Issa Abdoulahi; Bakasso Sahabi; Alio Sanda Abdelkader; Ilagouma Amadou Tidjani; Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J. Dis. Med. Plants 2020, 6(4), 92-97. doi: 10.11648/j.jdmp.20200604.15

Copy | Download

AMA Style

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J Dis Med Plants. 2020;6(4):92-97. doi: 10.11648/j.jdmp.20200604.15

Copy | Download

@article{10.11648/j.jdmp.20200604.15,
  author = {Mahamane Idi Issa Abdoulahi and Bakasso Sahabi and Alio Sanda Abdelkader and Ilagouma Amadou Tidjani and Yaou Chaïbou and Moctar Chaibou and Adamou Ibrahim Maman Laouali and Kiendrebeogo Martin and Sadou Hassimi},
  title = {Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {6},
  number = {4},
  pages = {92-97},
  doi = {10.11648/j.jdmp.20200604.15},
  url = {https://doi.org/10.11648/j.jdmp.20200604.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20200604.15},
  abstract = {Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.},
 year = {2020}
}

Copy | Download